Antibiotic of a wide spectrum of action. Antibiotic-azalide, a representative of a new subgroup of macrolide antibiotics. When creating a high inflammation in the focus of inflammation has a bactericidal effect.
Gram-positive cocci is sensitive to Azithromycin: Streptococcus pneumoniae, St. Pyogenes, St. Agalactiae, streptococcus groups CF and G, Staphylococcus aureus, St. Viridans; Gram-negative bacteria: Haemophilus influenzae, Moraxella catarrhalis, Bordetella pertussis, B. parapertussis, Legionella pneumophila, H. ducrei, Campylobacter jejuni, Neisseria gonorrhoeae and Gardnerella vaginalis; Some anaerobic microorganisms: Bacteroides bivius, Clostridium perfringens, Peptostreptococcus spp; As well as Chlamydia trachomatis, Mycoplasma pneumoniae, Ureaplasma urealyticum, Treponema pallidum, Borrelia burgdoferi. Azithromycin is inactive against gram-positive bacteria resistant to erythromycin.
Suction. Azithromycin is rapidly absorbed from the digestive tract, which is due to its resistance to acidic environment and lipophilicity. After oral administration of 500 mg of Azithromycin, the maximum concentration of azithromycin in the blood plasma is achieved after 2.5 -2.96 hours and is 0.4 mg / l. Bioavailability is 37%.