Cialis with Dapoxetine 60mg MALAY TIGER

10.00

Product: Cialis with Dapoxetine 60mg

Suitable for: Tadalafil

Package: 20/40 (10 pills)

SKU: 683 Category: Tag:

Description

Pharmacology

 

Pharmacological action – improving erectile function.

Erection with sexual stimulation is caused by increased blood flow to the tissues of the penis due to relaxation of the smooth muscles of the arteries and cavernous bodies.

This process is mediated by the release of nitric oxide from the nerve endings and endothelial cells of the cavernous bodies. Nitric oxide stimulates cGMP synthesis in smooth muscle cells. The accumulation of cGMP leads to muscle relaxation and increased blood flow to the cavernous bodies. Inhibition of PDE5 with tadalafil is accompanied by an increase in the amount of cGMP and increased erectile function. Since sexual stimulation is necessary to initiate the process of local release of nitric oxide, the inhibition of PDE5 by tadalafil in the absence of stimulation is not effective.

Therapeutic effects and effects Tadalafil is a drug that improves male erection. The drug has the ability to influence the key reactions that constitute a single process of sexual arousal and bringing the penis into an erect state. Usually, when a man is excited, the vessels of the penis widen greatly, an influx of a large volume of blood occurs, resulting in the penis becoming dense, that is, an erection (or, in the popular language, it “rises”). With various erectile dysfunctions, there is a defect in the blood filling of the vessels of the penis. Tadalafil is a drug that strengthens the blood filling of the penis, leading to a stable and good erection. The strengthened blood filling of the penis occurs due to the expansion of the vessels under the influence of a special substance – cGMP. But cGMP is rapidly destroyed by a special enzyme – cGMP-specific phosphodiesterase type 5 (PDE-5). Tadalafil inhibits (slows) the work of PDE-5, and as a result cGMP does not disintegrate, but a longer period of time, relaxing the blood vessels and helping to fill the penis with blood for the development of a normal erection. Thus, according to its clinical effect, Tadalafil is a vasodilator, or vasodilator.